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. 2022 Jan 17;17(3):939–943. doi: 10.1016/j.radcr.2022.01.014

Table 1.

Summary of cases of malignant transformation of DNTs.

Age (year) Sex Site Enhancement/Hemorrhage Pathology*
Present case 18 F P +/+ Anaplastic glioneuronal tumor
Matsumura et al. [4] 1 F P + / N/A Anaplastic glioneuronal tumor
Heiland et al. [5] 28 M O + / N/A Glioblastoma
Aggarwal et al. [6] 29 M Fr + / N/A Diffuse astrocytoma
Moazzam et al. [7] 22 F T + / N/A Oligoastrocytoma
Chuang et al. [8] 2 F Fr, P + / N/A Glioblastoma
Chao et al. [9] 15 F T + / N/A Diffuse astrocytoma
Mano et al. [10] 4 F F + / N/A DNT and anaplastic oligodendroglioma
Thom et al. [11] 56 M T + / N/A Anaplastic glioneuronal tumor
Ray et al. [12] 12 F Fr, P + / N/A Anaplastic astrocytoma
Tsuboi et al. [13] 35 F T + / N/A Anaplastic oligoastrocytoma
Hammond et al. [14] 29 M Fr + / N/A Glioblastoma
Gonzales et al. [15] 47 F Fr + / N/A Oligoastrocytoma
Rushing et al. [16] 14 M T, P N/A / N/A Anaplastic astrocytoma

DNT, dysembryoplastic neuroepithelial tumor; F, female; Fr, frontal lobe; M, male.

MRI, magnetic resonance imaging; N/A, not applicable; O, occipital lobe; P, parietal lobe; T, temporal lobe.

In the present case and the case of Mano et al. [10], primary tumors were malignant transformation of DNTs. In the other above cases, primary tumors were DNTs with WHO grade 1 and recurrent tumors were the above brain tumors with WHO grade 2, 3, or 4.