Table 1.
Summary of cases of malignant transformation of DNTs.
Age (year) | Sex | Site | Enhancement/Hemorrhage | Pathology* | |
---|---|---|---|---|---|
Present case | 18 | F | P | +/+ | Anaplastic glioneuronal tumor |
Matsumura et al. [4] | 1 | F | P | + / N/A | Anaplastic glioneuronal tumor |
Heiland et al. [5] | 28 | M | O | + / N/A | Glioblastoma |
Aggarwal et al. [6] | 29 | M | Fr | + / N/A | Diffuse astrocytoma |
Moazzam et al. [7] | 22 | F | T | + / N/A | Oligoastrocytoma |
Chuang et al. [8] | 2 | F | Fr, P | + / N/A | Glioblastoma |
Chao et al. [9] | 15 | F | T | + / N/A | Diffuse astrocytoma |
Mano et al. [10] | 4 | F | F | + / N/A | DNT and anaplastic oligodendroglioma |
Thom et al. [11] | 56 | M | T | + / N/A | Anaplastic glioneuronal tumor |
Ray et al. [12] | 12 | F | Fr, P | + / N/A | Anaplastic astrocytoma |
Tsuboi et al. [13] | 35 | F | T | + / N/A | Anaplastic oligoastrocytoma |
Hammond et al. [14] | 29 | M | Fr | + / N/A | Glioblastoma |
Gonzales et al. [15] | 47 | F | Fr | + / N/A | Oligoastrocytoma |
Rushing et al. [16] | 14 | M | T, P | N/A / N/A | Anaplastic astrocytoma |
DNT, dysembryoplastic neuroepithelial tumor; F, female; Fr, frontal lobe; M, male.
MRI, magnetic resonance imaging; N/A, not applicable; O, occipital lobe; P, parietal lobe; T, temporal lobe.
In the present case and the case of Mano et al. [10], primary tumors were malignant transformation of DNTs. In the other above cases, primary tumors were DNTs with WHO grade 1 and recurrent tumors were the above brain tumors with WHO grade 2, 3, or 4.