Table 1.
Baseline demographics and disease characteristics (Propensity Score–Matched Efficacy Set).
| Characteristic | Regdanvimab (n = 113) | Control (n = 161) | P value* |
|---|---|---|---|
| Age, years | |||
| Median (range) | 64.0 (26–90) | 63.0 (25–97) | 0.9221 |
| Female, n (%) | 41 (36.3) | 75 (46.6) | 0.0894 |
| BMI, kg/m2 | |||
| Mean (SD) | 24.2 (3.41) | 23.9 (3.50) | |
| <25, n (%) | 67 (59.3) | 92 (57.1) | 0.9873 |
| 25–29, n (%) | 27 (23.9) | 40 (24.8) | |
| >29, n (%) | 9 (8.0) | 14 (8.7) | |
| Missing, n (%) | 10 (8.8) | 15 (9.3) | |
| CCI, mean (SD) | 2.8 (1.95) | 2.7 (1.93) | 0.7522 |
| Severity of disease, n (%) | |||
| Asymptomatic or pre-symptomatic | 0 | 10 (6.2) | NA |
| Mild disease | 74 (65.5) | 110 (68.3) | |
| Moderate disease | 39 (34.5) | 41 (25.5) | |
| Symptom incidence, n (%) | |||
| Feeling feverish | 24 (21.2) | 34 (21.1) | NA |
| Shortness of breath or difficulty breathing | 35 (31.0) | 49 (30.4) | |
| Cough | 48 (42.5) | 59 (36.6) | |
| Diarrhea | 0 | 2 (1.2) | |
| Sputum | 20 (17.7) | 21 (13.0) | |
| Sore throat | 18 (15.9) | 30 (18.6) | |
| Loss of taste of smell | 2 (1.8) | 3 (1.9) | |
| Fatigue | 0 | 3 (1.9) | |
| Myalgia | 8 (7.1) | 19 (11.8) | |
| Widespread pain | 2 (1.8) | 2 (1.2) | |
| Nausea or vomiting | 1 (0.9) | 1 (0.6) | |
| Others | 7 (6.2) | 21 (13.0) | |
| Presence of pneumonia, n (%) | 39 (34.5) | 36 (22.4) | 0.0263 |
BMI, body mass index; CCI, Charlson Comorbidity Index; NA, not available; SD, standard deviation.
*
P value for covariates after propensity score matching, calculated from Student t test for continuous variables and chi-squared test for categorical variables.