Table 4:

Comparison of mesothelial and histiocytic macrophages.

Feature	Mesothelial macrophage	Histiocytic macrophage
Nucleus	Round to oval	Reniform (bean-, kidney-shaped)
Nuclear location	Central (most frequently)	Eccentric (most frequently)
Nuclear border close to the cell border	Absent	May be
Cell border	Sharp, smooth	Not well defined
Cytoplasmic blebs	Present	Absent
Cohesive sheets with distinct cell borders	Present	Absent
Margins of cell aggregates	Knobby	Ill-defined, irregular
Immunocytochemistry	Calretinin: nuclear or nuclear and cytoplasmic immunoreactivity Cytokeratin 7: cytoplasmic immunoreactivity D2-40: cytoplasmic immunoreactivity HBME-1: membranous immuno- reactivity along cell membrane	Immunoreactivity for CD45 (LCA), CD68 (PG-M1 and KP1), and CD163