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. 2022 Jan 31;7(2):251–261. doi: 10.1038/s41564-021-01054-z

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 10 — Correlation between isolate sampling time in months (x-axis) and phylogenetic root-to-tip divergence (y-axis), as estimated by TempEst based on ML phylogeny of each subclade. The two datasets correspond to S. flexneri serotype 2a isolates belonging to node A (A) and S. flexneri serotype 2b isolates belonging to node B (B) from PG3 in Supplementary Fig. 12. The linear regression line is coloured in red, with the coefficient of determination (R²) and p-value displayed for each plot.

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