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. 2022 Jan 31;7(2):251–261. doi: 10.1038/s41564-021-01054-z

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — The unrooted S. flexneri phylogenetic tree is shown with the five phylogroups (PG1–PG7) and Sf6 labelled accordingly. For each genomic subtype, monophyletic clusters of the dominant serotype are shown collapsed into bubbles coloured according to the inlaid key. Single isolate or groups of isolates within a subtype of an alternative serotype are represented by further branches, indicating a single serotype switch. The dashed rectangles group together multiple serotypic clusters belonging to the same PG. Bubble size indicates the number of isolates within a single cluster.