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. 2022 Jan 13;7(2):200–212. doi: 10.1038/s41564-021-01039-y

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 7 — a. Gene synteny showing 1) an additional genomic region with truncated, fragmented sequences homologous to one of the giant genes in Aloposons, and 2) tandem giant genes which show high homologies with their neighbors are found in Thorarchaeotes, and are distantly related to one of the two giant genes in Aloposons. b. Giant proteins larger than 3000 a.a. encoded by selected Asgard archaea representatives. In dark grey are part of the Aloposons. Functional domains as identified through conserved domain database (CDD) analyses are indicated on the right. Purple indicates genomes constructed in this study.