Table. 1.
Metabolic parameters of ApoE−/−PFKFB3fl/fl and ApoE−/−PFKFB3ECKO mice
| Metabolic parameters | ApoE−/−PFKFB3fl/fl | ApoE−/−PFKFB3ECKO |
|---|---|---|
| Liver enzymes | ||
| γ-Glutamyltransferase (U/L) | 5.5 ± 0.6 | 5 ± 0.4 |
| Alanine transaminase (U/L) | 39 ± 11 | 34 ± 6 |
| Alkaline phosphatase (U/L) | 132 ± 13 | 154 ± 13 |
| Fasting blood glucose (mg/dL) | 116 ± 4 | 100 ± 8 |
| Non-fasting blood glucose (mg/dL) | 152 ± 9 | 138 ± 10 |
| Insulin (ng/ml) | 0.2 ± 0.1 | 0.2 ± 0.1 |
| Total cholesterol (mg/dL) | 306 ± 2 | 317 ± 1 |
| Body weight (g) | 20 ± 0.4 | 19 ± 0.3 |
| Triglycerides (mg/dL) | 79 ± 23 | 57 ± 6 |
| β-hydroxybutyrate (µM) | 1.9 ± 0.2 | 2.0 ± 0.1 |
Data between ApoE−/−PFKFB3ECKO and ApoE−/−PFKFB3fl/fl mice are not significantly different. Independent Sample t test, n = 8 (ApoE−/−PFKFB3fl/fl) or n = 11 (ApoE−/−PFKFB3ECKO)