TABLE 1.
GSK-3 inhibitors.
| Type/class | Compound |
| ATP competitive | |
| Indoles | BIO, indirubin-3’-oxime |
| Maleimides | SB-216763, SB-415286 |
| BIP-135 | |
| Pyridines and pyrimidines | CHIR98014, CHIR98023, CHIR99021 |
| AZD1080, SAR502250 | |
| IMID1, IMID2 | |
| TWS119 | |
| AZD1080, SAR502250 | |
| JGK-263 | |
| Thiazole | AR-A014418 |
| VP2.51, VP2.54 | |
| Paullones | Kenpaullone, Alsterpaullone, Cazpaullone, Azakenpaullone |
| Pyrazine | AZD2858 |
| Oxadiazole | MMBO, TCS2002 |
| Isonicotinamides | Compounds 19, 25, and 33 |
| Oxazole-carboxamide | PF-04802367 (PF-367) |
| Pyrazolodihydropyridine | BRD0705, BRD3731 |
| indazole-carboxamide | AF3581 |
| Non-ATP competitive | |
| Thiadiazolidinones | TDZD-8, Tideglusib (NP031112, NP-12) |
| VP0.7, VP3.35, SC100 | |
| Chloromethyl thienyl and halomethyl phenyl ketones | GSK-3β Inhibitor VI |
| Substrate competitive | |
| Peptides | L803mt, L807mts |
| Anthracenone–isoxazole | 4-1, 4-2, 4-3, 4-4, 4-5 |
| Iminothiadiazoles | 5-imino-1,2,4-thiadiazoles, VP 1.14, VP 1.16 |
Inhibitors are sorted by mode of inhibition and chemical cores.