Table 1.
General characteristics of studies.
References | Study type | Participants (n) | Follow-up (weeks) | Probiotic type | Study conclusions |
---|---|---|---|---|---|
Jamali et al. (20) | Randomized Controlled Clinical Trial | n = 99 | 12 weeks | SS K12 | Probiotic therapy following oral disinfection with chlorhexidine may reduce the severity of halitosis over longer periods. |
Benic et al. (21) | Randomized, triple-blind, placebo-controlled trial | n = 64 | 12 weeks | SS M18 | Oral probiotic SS M18 reduced the level of halitosis in patients wearing orthodontic. |
He et al. (22) | Randomized, placebo-controlled trial | n = 28 | 4 weeks | SS K12 | The use of SS K12 did not have significant effect on halitosis with tongue coating cause when the tongue coating was not physically or chemically pre-treated, which implies removing tongue coating is required before SS K12 use. |
Lee et al. (23) | Randomized, double-blind, placebo-controlled study | n = 92 | 8 weeks | WC | WC tablets could prove to be a safe and useful oral care product to control bad breath. |
SS, Streptococcus salivarius, WC, Weissella cibaria.