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. 2022 Jan 21;8:787908. doi: 10.3389/fnut.2021.787908

Table 1.

General characteristics of studies.

References Study type Participants (n) Follow-up (weeks) Probiotic type Study conclusions
Jamali et al. (20) Randomized Controlled Clinical Trial n = 99 12 weeks SS K12 Probiotic therapy following oral disinfection with chlorhexidine may reduce the severity of halitosis over longer periods.
Benic et al. (21) Randomized, triple-blind, placebo-controlled trial n = 64 12 weeks SS M18 Oral probiotic SS M18 reduced the level of halitosis in patients wearing orthodontic.
He et al. (22) Randomized, placebo-controlled trial n = 28 4 weeks SS K12 The use of SS K12 did not have significant effect on halitosis with tongue coating cause when the tongue coating was not physically or chemically pre-treated, which implies removing tongue coating is required before SS K12 use.
Lee et al. (23) Randomized, double-blind, placebo-controlled study n = 92 8 weeks WC WC tablets could prove to be a safe and useful oral care product to control bad breath.

SS, Streptococcus salivarius, WC, Weissella cibaria.