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. 2022 Jan 21;15:784045. doi: 10.3389/fncel.2021.784045

Figure 3.

Figure 3

Acute and long-term effects of intermittent hypoxia (IH) on the firing of CA1 putative interneurons. (A) Repeated measured ANOVA revealed that neuronal firing was not significantly affected in control group. (B) Summary of the mean firing rates of putative interneurons recorded in the three recording sessions in each day over the 2-week period. Apart from the significantly elevated firing of the putative interneurons after 8 h of IH treatment in some days of the first week, the major effect of the chronic intermittent hypoxia was a strong suppression of firing found in the second week of IH treatment. (C) The up panel shows typical raster plots of the putative interneurons recorded before IH on day 1, 2, 7 and 14. Statistical results are shown on the bottom. (D) Typical raster plots of the putative interneurons recorded in the first 5 IH min of IH treatment on day 1, 2, 7 and 14 are shown on the up and the mean data are summarized on the bottom. (E) Typical raster plots of the putative interneurons recorded in the last 5 IH mins of IH treatment on day 1, 2, 7 and 14 are shown on the up and the mean data are summarized on the bottom. *P < 0.05, ** P < 0.01, ***P < 0.001.