Table 4.
Post-transplant perioperative complications.
| Characteristic | SCS SCD N = 45 |
SCS ECD N = 21 |
EVLP N = 22 |
P-value (KW or χ2) |
|---|---|---|---|---|
| Reintervention a | 7 (15.6%) | 3 (14.3%) | 5 (22.7%) | 0.71 |
| Surgical | 6 (13.3%) | 3 (14.3%) | 5 (22.7%) | 0.60 |
| Radiologic | 1 (2.2%) | 0 (0.0%) | 0 (0.0%) | 0.62 |
| Grade 3 PGD at 72 hours b | 9/41 (22.0%) | 3/18 (16.7%) | 6/21 (28.6%) | 0.67 |
| N Excluded (Ungradablec) | 1 (2.2%) | 1 (4.8%) | 0 (0.0%) | |
| N Excluded (Data Unavailable) | 3 (6.7%) | 2 (9.5%) | 1 (4.5%) | |
| Post-operative ECMO | 7 (15.6%) | 3 (14.3%) | 4 (18.2%) | 0.94 |
| Extubated in >48 hours | 15 (33.3%) | 3 (14.3%) | 10 (45.5%) | 0.09 |
| Tracheostomy within 7 days | 8 (17.8%) | 2 (9.5%) | 5 (22.7%) | 0.51 |
| Reintubated d | 4 (8.9%) | 5 (23.8%) | 6 (27.3%) | 0.11 |
| Renal replacement therapy d | 5 (11.1%) | 3 (14.3%) | 5 (22.7%) | 0.45 |
| ICU readmission a | 5 (11.1%) | 3 (14.3%) | 4 (18.2%) | 0.72 |
| Hospital readmission a | 11 (24.4%) | 8 (38.1%) | 5 (22.7%) | 0.40 |
| Post-transplant ICU LOS (days) | 3 [2, 8] | 5 [2, 11.5] | 6 [3.8, 20.5] | 0.10 |
| Post-transplant hospital LOS (days) | 20 [14.5, 33.5] | 24 [15, 30] | 27 [18, 56.8] | 0.26 |
| Acute rejection a | 11 (24.4%) | 6 (28.6%) | 3 (13.6%) | 0.47 |
| Mortality within 90 days | 1 (2.2%) | 1 (4.8%) | 1 (4.5%) | 0.82 |
Median (interquartile range) for continuous variables and count (percent) for categorical variables.
ECD, extended-criteria donor. ECMO, extracorporeal membrane oxygenation. EVLP, ex-vivo lung perfusion. ICU, intensive care unit. LOS, length of stay. PGD, primary graft dysfunction. SCD, standard-criteria donor. SCS, static cold storage.
Within 30 days.
A total of 82/88 patients were included in the analysis of grade 3 primary graft dysfunction at 72 hours, excluding 6 patients for whom primary graft dysfunction could not be graded either due to ECMO status (see footnote c) or data missingness. Patients who were on extracorporeal membrane oxygenation support and had radiographic evidence of pulmonary edema at 72 hours post-transplant were classified as having grade 3 primary graft dysfunction per International Society for Heart and Lung Transplantation guidelines.
In accordance with International Society for Heart and Lung Transplantation guidelines, patients who were on extracorporeal membrane oxygenation support and had no radiographic evidence of pulmonary edema at 72 hours post-transplant were designated as “ungradable” and excluded from the analysis of 72-hour primary graft dysfunction.
During index transplant hospitalization.