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. Author manuscript; available in PMC: 2023 Feb 2.
Published in final edited form as: Neuron. 2021 Dec 2;110(3):470–485.e7. doi: 10.1016/j.neuron.2021.11.010

Fig. 2. ASH neurons’ adaptation to touch is mediated by glial CLH-1.

Fig. 2.

(A-F) Left panels, calcium transients generated in ASH neurons by two nose touch stimulations as measured by % increase of GCaMP-6s fluorescence above the baseline (ΔF/F) in wild type (A), clh-1(ok658) (B), CLH-1 rescue in ASH neurons (C), CLH-1 rescue in AMsh glia (D), deg-1(u38u421) (E), and trpa-1(ok999) (F) worms. Data are shown as mean ± SEM (light gray and red). The first touch is shown in black, the second in red. The number of animals tested is shown within each panel. The vertical dashed line shows when the touch stimulation was delivered. Middle panels, peak percentage (%) of GCaMP-6s ΔF/F. Right panels, GCaMP-6s fluorescence decay time constants. Individual data points are shown as open circles and columns represent mean ± SEM. Statistics were calculated by two-tailed unpaired t-Test (ns, not significant (p>0.05), *p<0.05, **p<0.01, ****p<0.0001).