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. 2022 Feb 3;13:668. doi: 10.1038/s41467-022-28265-0

Fig. 6. Schematic summary of DENR regulation in mitosis.

Fig. 6

During early stages of mitosis, DENR protein is stabilized via phosphorylation of Ser73 which enables it to promote translation of target genes involved in mitosis. As of anaphase, DENR phosphorylation on Ser73 decreases, concomitant with a caspase-dependent decrease in DENR protein levels as cells exit mitosis.