Table 2.

Discrimination power of other inflammatory and thromboinflammatory markers for severe outcome and comparison with galectin-3.

Biomarker	AUC	95% CI	p value	p value (comparison with galectin-3 AUC)
Galectin-3	0.75	(0.67–0.84)	< 0.0001	–
CRP	0.76	(0.68–0.85)	< 0.0001	0.70
Albumin	0.73	(0.65–0.82)	< 0.0001	0.93
NLR	0.71	(0.62–0.79)	< 0.0001	0.52
Neutrophil count	0.70	(0.61–0.78)	< 0.0001	0.43
Ferritin	0.66	(0.57–0.76)	< 0.01	0.19
Lymphocyte count	0.58	(0.49–0.68)	0.09	0.02
Platelets	0.48	(0.38–0.58)	0.66	< 0.01
D-Dimer	0.69	(0.60–0.79)	< 0.001	0.49
Fibrinogen	0.66	(0.57–0.75)	< 0.01	0.16
INR	0.61	(0.51–0.71)	0.04	0.05
Triglycerides	0.64	(0.54–0.74)	0.01	0.12
AST	0.68	(0.59–0.76)	< 0.001	0.27

ROC curves were performed to determine the discrimination power of each biomarker for severe outcome. The AUC obtained was compared against that of galectin-3 using DeLong’s test for correlated ROC curves. Bold values represent p < 0.05.