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. 2022 Jan 21;8:770975. doi: 10.3389/fcvm.2021.770975

Table 1.

The study characteristics of included studies.

References Title Subjects Intervention Index
Average age (n-n years) Male/ Female N Type of training Training frequency Content
Dalal et al. (43) Short-duration high-intensity interval exercise training is more effective than long duration for blood pressure and arterial stiffness but not for inflammatory markers and lipid profiles in patients with stage 1 hypertension 48.0 (43.0–53.8) 30/0 10 LVHIIT 3 times/week, 8 weeks 80%VO2max 27 × 30 s SBP (↓), DBP (↓)
10 LVHIIT 85%VO2max 4 × 4 min SBP (↓), DBP (↓)
10 Blank Blank SBP (↔), DBP (↔)
Bahmanbeglou et al. (44) The benefits of high-intensity interval training on cognition and blood pressure in older adults with hypertension and subjective cognitive decline: results from the heart & mind study 71.1 (63.3–78.0) 67/61 65 LVHIIT 3 times/week, 24 weeks 85–95% HRmax 25 min SBP (↓), Time to exhaustion (↑)
63 MIT 60–80% HRmax 25 min SBP (↓), Time to exhaustion (↑)
Lins-Filho et al. (49) Effects of interval training on blood pressure and endothelial function in hypertensive patients 51.3 (40.9–61.1) 8/6 7 LVHIIT 5 times/week, 4 weeks 80% HRmax 5 × 3 min SBP (↓), DBP (↓), BMI (↔), Rest HR (↓)
7 MIT 60% HRmax 35 min SBP (↓), DBP (↔), BMI (↔), Rest HR (↔)
Whitaker et al. (37) Effects of different aerobic exercise programs with nutritional intervention in sedentary adults with overweight/obesity and hypertension: EXERDIET-HTA study 54.0 (44.4–63.5) 120/55 40 MIT 2 times/week, 16 weeks 65% VO2max 45 min SBP (↓), DBP (↓), BMI (↓), Rest HR (↓), MBP (↓), Anaerobic thresholds (↔)
42 HVHIIT 95% VO2max 45 min SBP (↓), DBP (↓), BMI (↓), Rest HR (↓), MBP (↓), Anaerobic thresholds (↑)
41 LVHIIT 90% VO2max 20 min SBP (↓), DBP (↓), BMI (↓), Rest HR (↓), MBP (↓), Anaerobic thresholds (↑)
40 General physical activity General physical activity SBP (↓), DBP (↓), BMI (↓), Rest HR (↓), MBP (↓), Anaerobic thresholds (↔)
Boa Sorte Silva et al. (45) High-intensity interval training lowers blood pressure and improves apelin and NOx plasma levels in older treated hypertensive individuals 61.7 (51.1–69.3) 23/19 Unknown LVHIIT 3 times/week, 6 weeks 85–90% HRmax 35 min SBP (↓), DBP (↓), Rest HR (↔), Max VO2 (↑), Time to exhaustion (↑)
Unknown Blank blank SBP (↔), DBP (↔), Rest HR (↔), Max VO2 (↔), Time to exhaustion (↔)
Izadi et al. (46) Effects of high-intensity interval training vs. moderate-intensity continuous training on epicardial fat thickness and endothelial function in hypertensive metabolic syndrome 50.9 (42.6–60.3) 18/16 17 LVHIIT 3 times/week, 8 weeks 85% HRmax 5 × 3 min SBP (↓), DBP (↓), BMI (↓), Rest HR (↓), Total cholesterol (↓)
17 MIT 60 HRmax 35 min SBP (↓), DBP (↓), BMI (↓), Rest HR (↔), Total cholesterol (↔)
Sosner et al. (48) Affective responses to different prescriptions of high-intensity interval exercise in hypertensive patients 65.3 (61.1–69.5) 0/20 Unknown LVHIIT 8 times 80–85% VO2max 5 × 2 min SBP (↔), DBP (↔), Rest HR (↔)
Unknown Blank blank SBP (↔), DBP (↔), Rest HR (↓)
Gorostegi-Anduaga et al. (38) Effects of different aerobic exercise programs on cardiac autonomic modulation and hemodynamics in hypertension: data from EXERDIET-HTA randomized trial 53.7 (31.8–61.7) 158/91 61 HVHIIT 16 weeks 45 min SBP (↓), DBP (↓), Rest HR (↓), Max VO2 (↑)
62 LVHIIT 20 min SBP (↓), DBP (↓), Rest HR (↓), Max VO2 (↑)
60 MIT 45 min SBP (↓), DBP (↓), Rest HR (↓), Max VO2 (↑)
59 General physical activity General physical activity SBP (↓), DBP (↓), Rest HR (↓), Max VO2 (↔)
Soltani et al. (53) Effects of antihypertensive medication and high-intensity interval training in hypertensive metabolic syndrome individuals 58.7 (53.2–64.2) Unknown Unknown LVHIIT (Take Placebo) 3 times/week, 16 weeks 90% HRmax 4 × 4 min/5 × 5 min (Take Placebo) SBP (↔), DBP (↔), Rest HR (↔), Mean arterial pressure (↔)
Unknown LVHIIT (Take antihypertensive drug) 90% HRmax 4 × 4 min/5 × 5 min (Take antihypertensive drug) SBP (↔), DBP (↔), Rest HR (↓), Mean arterial pressure (↔)
Taha et al. (51) High-intensity interval training irrespective of its intensity improves markers of blood fluidity in hypertensive patients 48.0 (43.0–53.8) 30/0 10 LVHIIT 3 times/week, 8 weeks 80–100%VO2max 2 × 30 s SBP (↓), MAP (↔), BMI (↔)
10 LVHIIT 75–90%VO2max 4 × 4 min SBP (↓), MAP (↓), BMI (↔)
10 Blank Blank SBP (↔), MAP (↔), BMI (↔)
Jo et al. (47) Ambulatory blood pressure reduction following 2 weeks of high-intensity interval training on an immersed ergo cycle 65.0 (54.0–72.0) 22/20 Unknown LVHIIT 3 times/week, 2 weeks 100% Peak Power 2 × 15 s (Dryland) SBP (↔), BMI (↔), Rest HR (↔)
Unknown LVHIIT 100% Peak Power 2 × 15 s (Immersed) SBP (↓), BMI (↓), Rest HR (↓)
Unknown MIT 50%PeakPower SBP (↔), BMI (↔), Rest HR (↔)
Jo et al. (50) Effect of high-intensity interval training on endothelial function in postmenopausal hypertensive patients: a randomized controlled trial 48.0 (45.2–50.4) 0/46 23 LVHIIT 3 times/week, 10 weeks 80–85% HRmax 4 × 4 min SBP (↓), DBP (↓), BMI (↔)
23 Blank Blank SBP (↔), DBP (↔), BMI (↔)

Blank, Blank control; LVHIIT, low-volume high-intensity interval training; HVHIIT, high-volume high-intensity interval training; MIT, Medium intensity training; SBP, systolic blood pressure; DBP, diastolic blood pressure; BMI, body mass index; HR, heart rate; Max VO2, maximal oxygen consumption; ↑, Significantly rise; ↓, Significantly decrease; ↔, No statistically significant change.