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Clinical course and changes in concentrations of five different cytokines in serum during antirickettsial treatment of a patient with JSF. All cytokine levels are expressed as pg/ml. The limits of assay sensitivity were as follows: 0.5 pg/ml for TNF-α, IL-1β, and gamma interferon (IFN-γ); 0.78 pg/ml for IL-10; and 31.3 pg/ml for macrophage colony-stimulating factor (M-CSF). BT, body temperature; CPFX, ciprofloxacin hydrochloride.
