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. 2022 Feb 3;12:1887. doi: 10.1038/s41598-022-05957-7

Table 3.

Organ at risk dose parameters after transposition of breathhold plan (BH) to second breathhold (RBH) and failure ot breathhold (FTBH) CT anatomy.

ROI BH FTBH RBH
Dose (Gy) ± sd Dose (Gy) ± sd T-statistic P-value Dose (Gy) ± sd T-statistic P-value
Heart
D02 14.09 ± 8.93 24.46 ± 7.16 − 7.453  < 0.001 14.21 ± 8.93 − 0.528 0.604
Dmean 2.47 ± 0.97 3.96 ± 1.35 − 7.509  < 0.001 2.50 ± 0.98 1.076 0.296
V5 7.79 ± 5.68 16.87 ± 7.68 − 6.909  < 0.001 7.97 ± 5.88 − 1.147 0.265
V10 3.62 ± 3.61 9.59 ± 5.59 − 6.787  < 0.001 3.76 ± 3.62 − 1.656 0.114
V20 1.36 ± 1.62 3.96 ± 2.82 − 6.074  < 0.001 1.39 ± 1.65 − 0.369 0.716
V30 0.45 ± 0.57 1.44 ± 1.25 − 4.594  < 0.001 0.45 ± 0.57 0.127 0.900
LAD
D02 14.22 ± 10.16 21.22 ± 9.90 − 3.952  < 0.001 15.01 ± 9.80 − 1.323 0.201
Dmean 5.99 ± 4.19 8.33 ± 4.08 − 3.274 0.004 6.06 ± 3.94 − 0.514 0.613
V5 31.20 ± 25.57 48.45 ± 23.41 − 4.048  < 0.001 32.30 ± 24.50 − 0.922 0.368
V10 15.45 ± 20.14 27.50 ± 19.80 − 3.018 0.012 16.18 ± 19.69 − 0.861 0.400
V20 6.18 ± 14.28 10.03 ± 13.76 − 1.326 0.201 6.44 ± 13.22 − 0.527 0.604
V30 1.958 ± 5.30 2.52 ± 4.63 − 0.716 0.483 1.42 ± 4.20 − 1.784 0.090
Left lung
D02 32.23 ± 2.03 33.36 ± 2.62 − 3.083 0.006 32.09 ± 2.42 0.665 0.514
Dmean 4.46 ± 0.68 4.83 ± 0.68 − 3.604 0.002 4.39 ± 0.71 1.538 0.141
V5 21.67 ± 3.09 22.99 ± 3.06 − 2.856 0.010 19.85 ± 5.45 2.266 0.035
V10 14.13 ± 2.59 15.36 ± 2.69 − 3.301 0.004 13.88 ± 2.68 1.331 0.199
V20 7.31 ± 1.69 7.93 ± 1.71 − 2.250 0.037 7.14 ± 1.63 1.277 0.217
V30 2.86 ± 0.87 3.37 ± 1.13 − 2.790 0.012 2.86 ± 0.97 0.082 0.936
Right lung
D02 4.48 ± 3.12 4.44 ± 3.46 0.200 0.844 4.14 ± 3.04 2.351 0.030
Dmean 0.80 ± 0.54 0.87 ± 0.65 − 1.962 0.065 0.76 ± 0.55 2.022 0.057
V5 2.73 ± 4.44 3.06 ± 5.55 − 0.949 0.355 2.46 ± 4.40 2.712 0.014
V10 0.63 ± 0.83 0.61 ± 1.08 0.177 0.862 0.49 ± 0.81 1.837 0.082
V20 0.06 ± 0.18 0.01 ± 0.03 1.342 0.195 0.01 ± 0.03 1.194 0.247
V30 0.02 ± 0.07 0.00 ± 0.00 1.000 0.330 0.00 ± 0.00 1.000 0.330
Thyroid
D02 18.91 ± 11.21 20.10 ± 14.87 − 0.701 0.492 21.53 ± 12.09 − 2.179 0.042
Dmean 3.38 ± 1.79 4.24 ± 3.25 − 1.708 0.104 3.76 ± 2.08 − 1.657 0.114
V5 14.37 ± 9.27 17.28 ± 15.80 − 1.298 0.210 16.18 ± 10.92 − 1.360 0.190
V10 7.72 ± 6.87 11.10 ± 11.90 − 1.793 0.089 9.69 ± 7.92 − 1.905 0.072
V20 3.39 ± 4.48 6.04 ± 7.76 − 1.967 0.064 4.55 ± 4.93 − 2.034 0.056
V30 1.27 ± 2.42 2.88 ± 4.69 − 1.782 0.091 1.79 ± 2.61 − 2.170 0.043
Esophagus
D02 15.97 ± 4.64 22.37 ± 9.69 − 3.354 0.003 16.60 ± 7.72 − 0.547 0.591
Dmean 2.44 ± 0.77 3.41 ± 1.51 − 3.485 0.002 2.71 ± 1.57 − 1.179 0.253
V5 13.00 ± 7.00 16.14 ± 7.98 − 3.023 0.007 14.00 ± 10.97 − 0.767 0.452
V10 6.71 ± 4.33 10.54 ± 6.36 − 3.411 0.003 7.82 ± 7.49 − 1.111 0.281
V20 1.10 ± 0.97 3.92 ± 4.08 − 3.228 0.004 1.78 ± 2.59 − 1.365 0.188
V30 0.04 ± 0.08 1.36 ± 2.28 − 2.584 0.018 0.34 ± 1.11 − 1.216 0.239
Contralateral breast
D02 5.28 ± 2.32 5.57 ± 2.62 − 1.449 0.164 5.47 ± 2.48 − 2.130 0.046
Dmean 1.11 ± 0.45 1.12 ± 0.48 − 0.675 0.508 1.12 ± 0.46 − 2.112 0.048
V5 3.17 ± 2.88 3.23 ± 3.21 − 0.328 0.746 3.23 ± 2.86 − 0.898 0.381
V10 0.034 ± 0.51 0.48 ± 0.67 − 2.446 0.024 0.42 ± 0.62 − 1.568 0.133
V20 0.01 ± 0.03 0.02 ± 0.08 − 1.231 0.233 0.01 ± 0.04 − 1.000 0.330

Tests report comparisons of either FTBH or RBH to BH.

ROI region of interest, LAD left anterior descending coronary artery, sd standard deviation, Dxx minimum dose received by xx% of ROI volume, Vxx volume percentage receiving at least xx Gy, Dmean mean dose delivered to ROI volume.