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. 2022 Feb 3;13:675. doi: 10.1038/s41467-022-28273-0

Table 1.

Patient demographics.

UCSF Mount Sinai
Overall AD Control SMD Overall AD Control SMD
n 26,412 8804 17,608 17,874 5958 11,916
Sex, n (%)
  Female 16,675 (63.1) 5558 (63.1) 11,117 (63.1) <0.001 12,584 (70.4) 4138 (69.5) 8446 (70.9) 0.031
  Male 9659 (36.6) 3220 (36.6) 6439 (36.6) 5290 (29.6) 1820 (30.5) 3470 (29.1)
  Unknown 78 (0.3) 26 (0.3) 52 (0.3)
 Estimated age, mean (SD) 86.5 (6.4) 86.5 (6.4) 86.5 (6.4) <0.001 88.6 (10.6) 88.3 (8.7) 88.7 (11.4) −0.039
Race, n (%)
  American Indian/Alaska Native 27 (0.1) 9 (0.1) 18 (0.1) <0.001 20 (0.1) 8 (0.1) 12 (0.1) 0.129
  Asian 2638 (10.3) 879 (10.3) 1759 (10.3) 177 (1.0) 78 (1.3) 99 (0.8)
  Black/African American 1758 (6.9) 586 (6.9) 1172 (6.9) 3732 (20.9) 1214 (20.4) 2518 (21.1)
  Native Hawaiian/Pacific Islander 1356 (5.3) 452 (5.3) 904 (5.3) 9 (0.1) 5 (0.1) 4 (0.0)
  Other 2230 (8.7) 743 (8.7) 1487 (8.7) 3922 (21.9) 1496 (25.1) 2426 (20.4)
  Unknown 2017 (7.6) 673 (7.6) 1344 (7.6) 786 (4.4) 253 (4.2) 533 (4.5)
  White/Caucasian 16,386 (64.0) 5462 (64.0) 10,924 (64.0) 9228 (51.6) 2904 (48.7) 6324 (53.1)
Death status, n (%)
  Alive 20,146 (76.3) 6714 (76.3) 13,432 (76.3) 0.001 9371 (52.4) 3264 (54.8) 6107 (51.3) 0.078
  Deceased 6266 (23.7) 2090 (23.7) 4176 (23.7) 882 (4.9) 306 (5.1) 576 (4.8)
  Unknown 7621 (42.6) 2388 (40.1) 5233 (43.9)

Summary table of sex, estimated age, death status, and first race among Alzheimer’s and control cohorts at UCSF and Mount Sinai. Patients are propensity score-matched at a 1:2 Alzheimer to control ratio with the demographics shown in the table.

SD standard deviation, SMD standardized mean difference.