Table 1.

Summary of published studies on the prevalence of CH mutations from plasma cfDNA analysis in patients with GI cancers.

Study	Study population	Cancer type	Sequencing method	Gene panel	Prevalence of CH detection from plasma cfDNA analysis
Chan et al. (32)	38	Colorectal cancer	Targeted NGS	52 genes	17%
Leal et al. (28)	50	Gastric cancer	Targeted NGS	58 genes	52%
Huang et al. (33)	236	Metastatic colorectal cancer	Targeted NGS and ddPCR	4 genes	1.27%
Ococks et al. (35)	97	Esophageal cancer	Targeted NGS	77 genes	23%