Kaplan–Meier survival curves without a landmark (1A) and using a 6-month landmark analysis (1B). For the conditional landmark analysis, 2444 patients did not survive until the 6-month landmark and were excluded. Of the 4512 remaining patients, 707 developed thyroiditis within 6 months, whereas 3805 patients either never developed thyroiditis or developed it after the 6-month landmark. Most patients received programmed cell death protein 1 (PD-1)/programmed death-ligand 1 (PD-L1) inhibitors (87%), cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) inhibitors (5%), and 8% received combined PD-1/CTLA-4.
HR, hazard ratio.