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. 2022 Jan 30;76:103850. doi: 10.1016/j.ebiom.2022.103850

Figure 5.

Fig 5

Image-guided surgery of human breast cancer PDX models. TNBC PDX cells were inoculated into the fourth abdominal fat pad. Twenty-four hours after NIR agent injection (a, ICG-p28, b, ICG alone), the tumours were resected under visualization with the PDE imaging unit. White light photographs (left) and snapshot NIR PDE images are shown (right; dorsal view, greyscale at 800 nm). Yellow arrowhead: tumour. c, The signal-to-noise ratio in PDX-bearing mice was recorded with the PDE unit and quantitatively analysed (N = 8 per group). ***: P < 0.001 (t-test). The results are presented as the mean+SD.