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. 2022 Jan 21;13:811952. doi: 10.3389/fimmu.2022.811952

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Copyright © 2022 Kurano, Ohmiya, Kishi, Okada, Nakano, Yokoyama, Qian, Xia, He, Zheng, Yu, Jubishi, Okamoto, Moriya, Kodama and Yatomi

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Differences in antibody titers among COVID-19 patients classified by the disease maximum severity. We compared the titers of different types of antibodies among COVID-19 patients classified according to the disease maximum severity as described in the Material and Methods section, measured on day 4-5, day 6-7, day 8-9, day 10-11, day 12 after symptom onset. *P < 0.05, **P < 0.01. The horizontal bar represents the median, the box bar represents the lower and upper quartiles, and the fine bar represents the minimum and maximum. (A) IgM(N), (B) IgM(S1), (C) IgM(RBD), (D) IgG(N), (E) IgG(S1), (F) IgG(RBD), (G) IgA(N), (H) IgA(S1), (I) IgA(RBD).