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. 2022 Jan 21;12:806902. doi: 10.3389/fmicb.2021.806902

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Copyright © 2022 Zhu, Du, Wang, Huang, Hu, Lu, Li, Zhu, Qu, Cai, Liu and Du.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The embryos of SARS-CoV-2 infection in pregnant mice. (A) Embryo resorption rates between and uninfected control (CTR, n = 8) and infected pregnant (n = 17). (B) The typical graph of embryo development between uninfected (upper, E14.5) and infected (lower, E13.5). The site that the arrow pointed at was the uterine horn. (C) Further splitting the pregnant group into two groups by E4.5 (infected before E 4.5, n = 7 vs. infected after E 4.5 n = 10), the real pregnant rates after plugged (the numbers of pregnant mice/the numbers of plugged per experiment) were displayed. (D) Based on the prior group, the embryo resorption rates were compared. ns p > 0.05, ^*p < 0.05, and ^**p < 0.01.