Table 3.
Differences in biochemical markers of patients with CLL (N = 22) before and during the DI2 with High OC/OL-EVOO. a
| Biochemical Marker | 6 months before a Median (min–max) |
3 months before b Median (min–max) |
Baseline c Median (min–max) |
3 months after d Median (min–max) |
6 months after e Median (min-max) |
p-value (adj) |
|---|---|---|---|---|---|---|
| Glucose (mg/dl) |
103.00 (86.00–123.00) |
103.50 (86.00–138.00)) |
104.00 (62.00–132.00) |
100.00 (58.00–125.00) |
98.00 (74.00–120.00) |
b–e 0.039
c–e 0.018 |
| Urea (mg/dl) |
40.00 (25.00–68.00) |
41.50 (30.00–83.00) |
43.50 (30.00–85.00) |
40.00 (32.00–76.00) |
40.00 (30.00–60.00) |
0.154 |
| Uric Acid (mg/dl) |
5.40 (3.00–830) |
5.40 (2.80–7.10) |
5.50 (3.20–53.00) | 5.53 (3.10–8.60) |
5.20 (2.80–8.50) |
0.578 |
| Creatinin (mg/dl) |
1.00 (0.70–1.20) |
0.94 (0.60–1.40) |
0.92 (0.60–1.40) |
0.89 (0.70–1.40) |
0.90 (.60–1.45) |
0.061 |
| SGPT (U/L) |
19.00 (11.00–66.00) |
19.50 (8.00–46.00) |
18.50 (8.00–34.00) |
21.50 (10.00–74.00) |
15.00 (8.00–35.00) |
0.083 |
| SGOT (U/L) |
24.00 (14.00–51.00) |
25.00 (13.00–54.00) |
26.40 (13.00–40.00) |
22.67 (11.00–47.00) |
22.00 (12.00–38.00) |
0.329 |
| LDH (IU/L) |
201.00 (104.00–616.00) |
217.00 (104.00–576.00) |
213.00 (128.00–596.00) |
234.50 (164.00–445.00) |
227.50 (150.00–641.00) |
0.058 |
| γGT (U/L) |
15.00 (10.00–38.00) |
16.00 (9.00–45.00) |
15.00 (9.00–39.00) |
16.33 (10.00–37.00) |
15.00 (7.00–39.00) |
0.149 |
| ALP (U/L) |
73.00 (47.00–90.00) |
71.00 (38.00–240.00) |
69.00 (46.00–220.00) |
81.00 (42.00–198.00) |
75.00 (34.00–198.00) |
c–d 0.024
c–e 0.039 |
| Lipidemic Profile | ||||||
| Total cholesterol (mg/dl) | 197.00 (137.00–277.00) |
196.50 (137.00–255.00) |
185.50 (140.00–305.00) |
185.50 (125.00–300.00) |
190.00 (125.00–286.00) |
0.274 |
| Triglycerides (mg/dl) |
108.50 (46.00–250.00) |
114.00 (49.00–256.00) |
115.50 (63.00–299.00) |
109.00 (45.00–298.00) |
97.00 (67.00–280.00) |
0.955 |
| HDL cholesterol (mg/dl) | 60.50 (34.00–92.00) |
59.50 (36.00–108.00) |
58.67 (33.00–99.00) |
56.67 (16.00–98.00) |
57.00 (35.00–82.00) |
0.103 |
| LDL cholesterol (mg/dl) | 114.50 (72.00–185.00) |
113.00 (70.00–182.00) |
101.00 (68.00–212.00) |
111.00 (73.00–190.00) |
110.00 (68.00–200.00) |
0.428 |
a
Analysis was carried using Friedman test and Dunn–Bonferroni post hoc tests.
Bold emphasize statistical significant values.