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Comparison of AAD between humans and BAPN-administered mice
| Feature | Humans | BAPN-administered mice |
|---|---|---|
| Location | ||
| Aneurysm | Abdominal > thoracic aorta | Thoracic > abdominal aorta |
| Dissection | Thoracic aorta | Thoracic aorta |
| False lumen formation | Media | Media |
| Elastin fragmentation | Yes | Yes |
| Collagen deposition | Yes | Yes |
| Inflammatory cell accumulation | Yes | Yes |
AAD, Aortic aneurysm and dissection; BAPN, β-aminopropionitrile.
