Figure 2.

Sal improves the autonomous exploration activities of Aβ1-42 and D-gal/AlCl₃-induced AD mice. (A) The chemical structure diagram of Sal. (B,D,E) Mice autonomic capacity test, using open field test. (B) Sal or DNP treatment decreased the total distance, (D) reduced the average velocity, and (E) decreased time spent in the center within 5 min. (C) The representative motion track. All data are represented as mean ± SEM (n = 8/10). # Significantly different from the control-treated; significantly different from Aβ1-42 and D-gal/AlCl₃ treated. Significance = ^#p < 0.05, ^##p < 0.01 and ^###p < 0.001, ^*P < 0.05, ^**P < 0.01.