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. 2022 Jan 27;2022:9619357. doi: 10.1155/2022/9619357

Table 3.

Diagnostic marker panel derived from cfDNA samples.

DMR marker Coefficient Genomic location Gene XL-mHG p value
DMR_1 -0.007012253 chr1: 12493605-12494280 VPS13D 0.012529923
DMR_2 -0.293540674 chr1: 36983119-36983235 / 1.21307E-05
DMR_3 0.145449335 chr1: 248902767-248904167 LYPD8 0.0010886
DMR_4 -0.180719422 chr3: 11651536-11651990 VGLL4 0.001477124
DMR_5 0.3167126 chr4: 1195845-1196179 SPON2 0.00018493
DMR_6 0.194881649 chr5: 139043443-139044215 CXXC5 6.8938E-05
DMR_7 0.235620277 chr9: 123688715-123689193 TRAF1 2.2204E-16
DMR_8 0.29712874 chr11: 10476242-10477461 AMPD3 0.00183147
DMR_9 0.341871604 chr17: 16319861-16320257 TRPV2 6.4709E-04
DMR_10 0.236108117 chr17: 78753273-78754372 RPTOR 0.001784

DMR markers are made up of mean methylation values of CpG sites in the corresponding DMRs.