Fig. 1.

Stevens–Johnson syndrome/toxic epidermal necrolysis culprit drugs identified in Clalit, 2008–19, presented by the mean ALDEN score on the x-axis and the number of cases associated with the drug between January 2008 and June 2019 on the y-axis. Occurrence rate/10,000 new users of the drug in the community is represented by drug symbols, divided into three tertiles and into a fourth category of unknown rate (NA) (when the total number of new users was unknown for over-the-counter and in-patient medications). Two drugs with unknown ALDEN scores, celecoxib and carfilzomib, are not represented in the figure. To prevent the overlapping of drug symbols in the figure, random jittering around the accurate location of points was applied, with a distance up to ± 0.5