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. 2022 Jan 13;139(2):165–176. doi: 10.1182/blood.2021012788

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Figure 2. — Cholesterol, CE, and oxysterol synthesis. The main enzymes involved in cholesterol, CE, and oxysterol synthesis (red). HMG-CoA reductase, squalene synthase, and ACAT-1 enzymes are also the target of specific drugs. The pathway leading to isoprenoid formation is shown (green).