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. Author manuscript; available in PMC: 2022 Feb 4.
Published in final edited form as: Nature. 2021 Apr 29;595(7865):114–119. doi: 10.1038/s41586-021-03569-1

Fig. 4 |. Pathological fibroblasts and ensuing fibrosis in COVID-19.

Fig. 4 |

a, Coefficient of determination (R2) of days from symptom onset to death and fibrosis score in COVID-19 samples (n = 16, see Methods). Error bands, 95% s.e. interval on the Pearson correlation. b, UMAP of fibroblast (FB) sub-populations; insert indicates group assignments. path., pathological. c, Fractions of pathological fibroblasts among all fibroblasts in control (n = 7) and COVID-19 lungs (n = 19). Middle line, median; box edges, 25th and 75th percentiles; whiskers, most extreme points that do not exceed ±1.5 × IQR. Wilcoxon rank-sum test.