Table II.

Standardized measures of treatment effectiveness for areas relevant to goal domains

Measure	Baseline Mean (95% CI)	Change Mean (95% CI)	p-value vs baseline
Pain score (range 0-10)	n = 346	n =345	<0.001
	6.7 (6.5, 6.9)	-2.4 (-2.6, -2.2)
Associated Reaction Rating Scale (ARRS) (range 0-12)	n = 207	n =201	<0.001
	7.4 (7.0, 7.7)	-1.4 (-1.6, -1.1)
Arm Activity (ArmA) scores; Passive function (range 0-28)	n = 435	n = 429	<0.001
	14.1 (13.6, 14.6)	-2.9 (-3.3, -2.6)
Arm Activity (ArmA) scores; Active function (range 0-52)	n = 216	n =207	<0.001
	39.8 (38.4, 41.2)	-3.2 (-4.3, -2.2)
Functional Ambulation Category (FAC) scores	n = 32	n =30	0.071
	3.7 (3.24; 4.13)	0.3 (-0.1, 0.7)
ULS-NIS impaired mobility of joints*	n = 335	n =335
Proximal (shoulder and elbow)	1.8 (1.7, 2.0)	-0.2 (-0.3, -0.1)	<0.0001
Distal (wrist and hand)	2.3 (2.1, 2.5)	-0.4 (-0. 5, -0.2)	<0.0001

^*Paired t-test performed post-hoc. Scores are presented as the arithmetic mean of post-baseline scores across all evaluation cycles. Depending on in which areas goals were set at different visits, not all patients had both baseline and post-baseline assessments.

ULS-NIS: Upper Limb Spasticity adapted Neurological Impairment Scale.