Fig. 2.

ISarcoPRM diagnostic algorithm for sarcopenia. ISarcoPRM suggests to screen all older adults and adults with renin-angiotensin system (RAS)-related disorders by using ≥ 12 s for chair stand test (CST), and < 32 kg (males) and < 19 kg (females) for grip strength, < 1.0 (females) and < 1.4 (males) for sonographic anterior thigh ratio (Sonographic Thigh Adjustment Ratio; STAR) values. In the presence of sarcopenia, gait speed ≤0.8m/s and/or inability to rise from a chair without support is diagnosed as “severe sarcopenia”. *If any of the 2 tests (initially performed) is normal, it is suggested that the other test should be performed as well. If any of the 2 tests (initially performed) is abnormal, it is sufficient to proceed in the “low” direction. £Cognitive impairment, polyneuropathies, movement/balance disorders, depression or motivational problems etc. B: bone; M: muscle; F; subcutaneous fat tissue.