Table 2.

Statistical analysis of P21, P53, Bax, caspase-3, and Bcl-2 gene expression in melatonin-treated HepG2 cells and control using qRT-PCR analysis.

Gene Expression	Melatonin/HepG2 group	Control group	P
P21	2.3 (2.09–2.51)	1.00 (1.00–1.00)	<0.001∗
P53	13.05 (12.36–13.74)	1.00 (1.00–1.00)	<0.001∗
Bax	7.74 (7.36–8.12)	1.00 (1.00–1.00)	<0.001∗
Caspase-3	4.94 (4.68–5.2)	1.00 (1.00–1.00)	<0.001∗
Bcl-2	0.66 (0.62–0.7)	1.00 (1.00–1.00)	<0.001∗

P: Probability

∗: significance <0.05.

Mann whitney for data expressed as median (range).