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. 2022 Jan 20;23(3):231. doi: 10.3892/etm.2022.11155

Figure 2.

Figure 2

miR-146b-5p regulates the proliferation, migration, and invasion of HT29 and SW620 cells. HT29 and SW620 cells were transfected with the miR-146b-5p mimics or inhibitor. (A and B) Western blotting was used to determine the expression of cleaved-PARP and cleaved-caspase-3 in HT29 and SW620 cells. (C and D) Cell Counting Kit-8 assay was used to determine cell proliferation. (E and F) Transwell assay was used to evaluate the cell migration and invasion. Scale bar, 20 µm. (G and H) Quantification of Transwell assay from E and F. n=3. *P<0.05 vs. NC. NC, negative control; miR, microRNA; PARP, poly (ADP-ribose) polymerase.