Figure 3.
TRAF6 is lowly expressed in CRC tissue and cell lines. (A) Analysis of The Cancer Genome Atlas and Genotype-Tissue Expression databases showed that TRAF6 was expressed at low levels in most tumor tissue samples, including CRC. (B and C) Immunohistochemical and western blotting analyses of TRAF6 expression in CRC and normal adjacent tissue samples (n=19 pairs) and in CRC cell lines (n=3). Scale bar, 20 µm. *P<0.05 and **P<0.01. TRAF6, tumor necrosis factor receptor-associated factor 6; CRC, colorectal cancer.