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. 2022 Feb 4;15:1. doi: 10.1186/s13044-022-00120-w

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — Histological and immunohistochemical attributes of the synchronous papillary (PTC) and follicular thyroid carcinoma (FTC). All stains are hematoxylin–eosin unless otherwise specified. A The largest focus of the multifocal tall cell variant PTC is shown. Note the eosinophilic, taller-than-wide tumor cells and the “tram-track” appearance of tumor nuclei. B This lesion was positive for BRAF1, the V600 mutation specific antibody. C The 12 mm minimally invasive FTC (miFTC) was characterized by multiple areas with capsular invasion, but lacking angio-invasive features. D High-power magnification of the miFTC reveals monomorphic nuclei lacking PTC related changes