Table 3:

Sensitivity Analysis of Post-CPB Mean Urine Oxygen Partial Pressure Compared to Various Definitions of AKI in 86 Patients

	Number (%) of Patients with AKI	Unadjusted Relative Risk of AKI for Every 10mmHg Increase in Mean PuO2 (95% CI)	p	Unadjusted Relative Risk of AKI if Mean PuO2 < 25mmHg (95% CI)	p
Full KDIGO	53 (62%)	0.84 (0.73–0.99)	0.032	1.51 (1.08–2.10)	0.015
Oliguria Only	49 (57%)	0.89 (0.76–1.04)	0.149	1.08 (.61–1.92)	0.798
Creatinine Only	21 (24%)	0.92 (0.65–1.31)	0.650	2.46 (1.06–5.7)	0.036
KDIGO Stage 2/3	10 (12%)	0.70 (0.43–1.13)	0.147	3.70 (1.18–11.6)	0.025
Death or Kidney Injury at Discharge	11 (13%)	0.81 (0.50–1.31)	0.390	3.23 (1.06–9.9)	0.039

Comparisons were made using univariable binary Poisson regression with a robust standard error. AKI= acute kidney injury; 95% CI = 95% confidence interval. During the post-CPB period there were 9 patients who were excluded because of inadequate PuO2 data after filtering for low or invalid urine flows. AKI= acute kidney injury; 95% CI = 95% confidence interval; PuO2 = urine oxygen partial pressure; Baseline Cr = Baseline serum creatinine; Full KDIGO= creatinine elevation or oliguria based on the KDIGO guidelines; CPB = cardiopulmonary bypass.