Table 1.
Characteristics assessed by pathology report of 399 participants with diabetes who underwent kidney biopsy in the Pacific Northwest, including a subset of 79 with more extensive clinical data charted
| Sample Population | Cohort of N=399 Patients | Subset of N=79 Patients | ||
| No. with Data | Mean (SD) or N (%)a | No. with Data | Mean (SD) or N (%)a | |
| Demographics | ||||
| Age, yr, mean (SD) | 398 | 57.6 (13.1) | 78 | 53.6 (12.4) |
| Men | 398 | 230 (58) | 78 | 53 (68) |
| Race/ethnicity | ||||
| White | 130 | 71 (55) | 70 | 38 (54) |
| Black | 130 | 18 (14) | 70 | 10 (14) |
| Asian | 130 | 23 (18) | 70 | 10 (14) |
| Native American/Pacific Islander | 130 | 8 (6) | 70 | 5 (7) |
| Hispanic | 130 | 10 (8) | 70 | 7 (10) |
| Medical history | ||||
| AKI | 399 | 98 (25) | 79 | 26 (33) |
| Rapid decline in eGFR | 399 | 91 (23) | 79 | 23 (29) |
| SLE | 399 | 7 (2) | 79 | 4 (5) |
| Organ transplant | 399 | 12 (3) | 79 | 6 (8) |
| Diagnostic results | ||||
| Proteinuria | 399 | 312 (78) | 79 | 59 (75) |
| Nephrotic range | 399 | 196 (49) | 79 | 41 (52) |
| Hematuria | 399 | 80 (20) | 79 | 20 (25) |
| Abnormal serology | 399 | 78 (20) | 79 | 18 (23) |
| Monoclonal gammopathy | 399 | 33 (8) | 79 | 11 (14) |
| HCV antibody | 399 | 33 (8) | 79 | 16 (20) |
| Laboratory values | ||||
| Serum creatinine, mg/dl | 302 | 3.0 (2.5) | 77 | 2.9 (2.1) |
| eGFR, ml/min per 1.73 m2 | 301 | 35.7 (28.2) | 76 | 38.7 (29.3) |
| Proteinuria, g/da | 223 | 6.2 (5.1) | 67 | 5.7 (5.0) |
| HbA1c, % | 72 | 7.9 (2.5) | 59 | 7.8 (2.2) |
| Biopsy characteristics | ||||
| Biopsy size (LM) | 395 | 1.3 (0.4) | 79 | 1.2 (0.4) |
| No. of glomeruli | 399 | 18.7 (10.4) | 79 | 20.2 (11.0) |
HCV, Hepatitis C virus; HbA1c, hemoglobin A1c; LM, light microscopy.
a
Proteinuria from spot specimens was assumed to be equivalent to grams per day.