Increase proportion of arteriovenous fistula (AVF) failure (composite outcome of AVF abandonment, thrombosis, and failure to cannulate) with decrease in diastolic BP. The light gray line reflects an almost inverse linear relationship between diastolic BP and proportion of AVF failure on univariable logistic regression, and the dashed gray line represent the 95% confidence interval at each diastolic BP level. The black line shows a similar relationship between diastolic BP and proportion of AVF failure on multivariable analysis adjusted for female sex, age, region of recruitment, presence of diabetes, presence of peripheral vascular disease, presence of central venous catheter, use of calcium channel blockers, hemoglobin levels, randomization to aspirin, randomization to fish oil, type of AVF created, surgical expertise, and type of anesthesia use; the dotted black line represents the 95% confidence interval.