Table 3.

Multivariable logistic regression analysis of patient and surgical factors for individual outcome components, including AVF abandonment, thrombosis, and cannulation failure at 12 mo

Parameter	Abandonment (n=121)		Thrombosis (n=109)		Failure to Cannulate (n=212)
	Adjusted OR (95% CI)	P Value	Adjusted OR (95% CI)	P Value	Adjusted OR (95% CI)	P Value
Female sex	2.02 (1.27 to 3.20)	<0.01	1.16 (0.72 to 1.89)	0.54	1.74 (1.16 to 2.61)	0.01
Age (per 10 yr)	1.01 (0.86 to 1.19)	0.89	0.92 (0.77 to 1.08)	0.30	1.12 (0.97 to 1.29)	0.12
Diastolic pressure (per 10 mm Hg)	0.91 (0.76 to 1.08)	0.27	0.90 (0.75 to 1.07)	0.23	0.80 (0.68 to 0.93)	0.01
Region a
Australia/NZ/UK	Ref	0.66	Ref	0.54	Ref	0.04
Malaysia	1.18 (0.56 to 2.47)		1.30 (0.57 to 2.97)		0.50 (0.26 to 0.98)
Diabetes mellitus	0.87 (0.54 to 1.39)	0.55	0.70 (0.43 to 1.14)	0.15	0.92 (0.61 to 1.38)	0.69
Presence of PVD	3.24 (1.31 to 7.98)	0.01	2.46 (0.95 to 6.35)	0.06	0.92 (0.37 to 2.27)	0.85
Presence of CVC	1.03 (0.65 to 1.61)	0.91	0.77 (0.48 to 1.24)	0.27	1.66 (1.11 to 2.46)	0.01
Use of CCB	0.91 (0.58 to 1.42)	0.67	0.84 (0.53 to 1.32)	0.45	0.88 (0.60 to 1.29)	0.51
Hemoglobin	1.00 (0.99 to 1.01)	0.98	1.00 (0.99 to 1.02)	0.58	1.00 (0.99 to 1.01)	0.48
Randomization to aspirin
Randomized to placebo	Ref	0.16	Ref	0.26	Ref	0.44
Randomized to aspirin	0.71 (0.42 to 1.18)		0.99 (0.58 to 1.68)		0.93 (0.60 to 1.43)
Open-label aspirin	1.19 (0.70 to 2.02)		1.50 (0.86 to 2.63)		1.26 (0.78 to 2.03)
Randomization to fish oil use	1.00 (0.65 to 1.52)	>0.99	0.86 (0.56 to 1.33)	0.50	1.13 (0.78 to 1.63)	0.53
AVF type
Radiocephalic	Ref	0.05	Ref	0.23	Ref	0.04
Brachiocephalic	0.48 (0.29 to 0.81)		0.60 (0.35 to 1.02)		0.71 (0.46 to 1.10)
Brachiobasilic	0.95 (0.41 to 2.19)		0.56 (0.21 to 1.53)		2.24 (1.07 to 4.72)
Others	1.20 (0.20 to 7.15)		0.66 (0.07 to 5.82)		0.89 (0.18 to 4.53)
Surgeons
Registrar/residents	Ref	0.54	Ref	0.10	Ref	0.72
Consultant	0.85 (0.52 to 1.41)		0.65 (0.40 to 1.08)		1.08 (0.69 to 1.69)
Anesthesia
Regional/general anesthesia	Ref	0.42	Ref	0.48	Ref	0.80
Local anesthesia	1.30 (0.69 to 2.45)		0.78 (0.39 to 1.55)		1.08 (0.62 to 1.88)

Single imputation for missing values of individual outcome components was performed and described in detail in the primary outcome analysis (30). AVF, arteriovenous fistula; OR, odds ratio; NZ, New Zealand; UK, United Kingdom; Ref, reference; PVD, peripheral vascular disease; CVC, central venous catheter; CCB, calcium channel blocker.

^aAustralia, New Zealand, and United Kingdom region of recruitment was grouped when compared with Malaysian region of recruitment in this analysis.