Table 2.

Predictors of number of hypoglycemic events: univariate analysis

Univariate Variable	Comparison	Estimated Coefficient (SEM)	Unadjusted Rate Ratio (95% CI)	P Value
Age per 1 yr		0.01 (0.002)	1.01 (1.007 to 1.013)	0.0001
Sex	Female versus male	0.46 (0.03)	1.581 (1.481 to 1.688)	0.0001
Race	Asian versus white	−0.27 (0.05)	0.762 (0.687 to 0.846)	0.0001
	Black versus white	0.22 (0.04)	1.241 (1.14 to 1.35)	0.0001
Ethnicity	Hispanic versus not Hispanic	−22.19 (79.0)	Extremely small	0.99
Body mass index per one unit (kg/m2)		−0.04 (0.003)	0.963 (0.957 to 0.969)	0.0001
Years of kidney diseases (per yr)		−0.09 (0.004)	0.917 (0.909 to 0.925)	0.0001
Fasting blood glucose (per mg/dl)		−0.01 (0.0003)	0.989 (0.988 to 0.99)	0.0001
Serum creatinine (per mg/dl)		0.07 (0.008)	1.075 (1.058 to 1.092)	0.0001
Serum albumin (per g/L)		0.006 (0.001)	1.006 (1.005 to 1.008)	0.0001
eGFR (per ml/min)		−0.008 (0.001)	0.993 (0.99 to 0.995)	0.0001
Hemoglobin (per g/dl)		−0.22 (0.006)	0.805 (0.796 to 0.815)	0.0001
HbA1c (per 1%)		−0.38 (0.01)	0.687 (0.669 to 0.706)	0.0001
Serum fructosamine, µmol/L		−0.004 (0.003)	0.996 (0.995 to 0.997)	0.0001
Average blood glucose (per 1 mg/dl)		−0.02 (0.006)	0.977 (0.975 to 0.978)	0.0001
CAD	Yes versus no	0.21 (0.03)	1.231 (1.154 to 1.312)	0.0001
CHF	Yes versus no	0.44 (0.03)	1.552 (1.455 to 1.655)	0.0001
Hypertension	Yes versus no	0.88 (0.12)	2.409 (1.912 to 3.039)	0.0001
Stroke history	Yes versus no	0.16 (0.04)	1.177 (1.096 to 1.264)	0.0001
History of malignancy	Yes versus no	0.43 (0.05)	1.531 (1.386 to 1.692)	0.0001
Medications
Sulfonylureas	Yes versus no	0.15 (0.03)	1.157 (1.082 to 1.237)	0.0001
Any insulin	Yes versus no	0.67 (0.04)	1.949 (1.821 to 2.087)	0.0001
Insulin with SU	Yes versus no	1.18 (0.04)	3.267 (3.048 to 3.508)	0.0001
Oral other than SU	Yes versus no	−0.06 (0.03)	0.945 (0.887 to 1.008)	0.08

Outcome variable: number of >15 min events with glucose <60 mg/dl; n=80. HbA1c, hemoglobin A1c; CAD, coronary artery disease; CHF, congestive heart failure; SU, sulfonylureas.