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. 2022 Jan 21;8:816422. doi: 10.3389/fmed.2021.816422

Table 1.

Demographic, laboratory, and clinical characteristics of the subjects.

Healthy control SpA patients P value
(n = 70) (n = 65)
Age, yrs 33.5 (28.8–37.3) 29.0 (25.0–39.0) 0.288
Sex, male/female 59/11 61/4 0.102
PLT,109/L 232 (191–249) 253 (219–310) 0.043
Hb, g/L 148(139–156) 142(125–149) 0.010
ESR, mm/h 5(2–9) 21(7–53) <0.001
CRP, mg/L 0.4 (0.2–4.3) 7.5 (7.2–37.2) <0.001
D-dimer, mg/L 0.14 (0.11–0.32) 0.21 (0.13–0.73) 0.016
FIB, g/L 2.23 (1.83–2.60) 3.10 (2.31–4.19) <0.001
PT, s 11.6 (11.2–12.3) 11.7 (11.2–12.4) 0.628
APTT, s 30.5 (29.4–32.3) 31.0 (29.8–33.6) 0.169
TT, s 17.3 (16.9–17.7) 17.7 (17.0–18.6) 0.100
axSpA/pSpA 56/9
HLA-B27 positivity, n (%) 58 (89.2)
Sacroiliitis, n (%) 56 (86.2)
Peripheral joint involvement, n (%) 31(47.7)
Peripheral arthritis 29
Enthesitis 5
Dactylitis 6
GI symptoms, n (%) 9 (13.8)
Anterior uveitis, n (%) 4 (6.2)
Psoriasis, n (%) 0(0)
Gut inflammation, n (%) 23 (35.4)

PLT, platelet; Hb, hemoglobin; ESR, erythrocyte sedimentation rate; CRP, C-reactive protein; FIB, fibrinogens; PT, prothrombin time; APTT, activated partial thromboplastin time; TT, thrombin time; HLA-B27, Human Leukocyte Antigen B27; GI, gastrointestinal. Bolded values indicate P < 0.05.