Table 1.

Clinical gene sets

Clinical Gene Sets
Atypical hemolytic uremic syndrome, thrombotic microangiopathy, and C3 glomerulopathy gene set (13 genes and CFHR3-CFHR1 deletion status)
ADAMTS13, C3, CD46, CFB, CFH, CFHR1, CFHR2, CFHR3, CFHR4, CFHR5, CFI, DGKE, and THBD; CFHR3-CFHR1 deletion by multiplex ligation-dependent probe amplification
Alport syndrome gene set (3 genes)
COL4A3, COL4A4, and COL4A5
Cystic disease and nephronophthisis gene set (23 genes)
AHI1, CEP290, GLIS2, INVS, IQCB1, NEK8, NPHP1, NPHP3, NPHP4, RPGRIP1L, TMEM67, TTC21B, XPNPEP3, BICC1, CRB2, EYA1, HNF1B, PAX2, PKD1, PKD2, PKHD1, SIX5, and UMOD.
Nephrotic syndrome and FSGS gene set (34 genes)
ACTN4, ADCK4 (COQ8B), ANLN, APOL1, ARHGAP24, ARHGDIA, CD2AP, COL4A3, COL4A4, COL4A5, COQ2, COQ6, CRB2, CUBN, EMP2, INF2, ITGA3, ITGB4, LAMB2, LMX1B, MEFV, MYH9, MYO1E, NEIL1, NPHS1, NPHS2, PDSS2, PLCE1, PTPRO, SCARB2, SMARCAL1, TRPC6, TTC21B, and WT1.