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Oxycodone intake per session across all doses in females from seven inbred strains (n=6–8 per strain), using an intermittent oral operant protocol. All strains increased intake across doses (p<0.001). The range of intakes at the final concentration of oxycodone (0.2 mg/ml) was 0.72±0.17 – 4.84±1.42 mg/kg (mean ± SEM), a 6.7-fold difference across strains. At 0.2 mg/ml, female LEW rats obtained 2.75 mg/kg/session - a 25-fold increase from the initial intake levels.
