TABLE 4.

Association of ln plasma aldosterone concentration with estimated glomerular filtration rate in multivariate linear regression models

Model	B coefficients (95% CI)	P	Minimum Tolerance	Maximum VIF
Crude	–7.71 (–11.70, –3.73)	< 0.001	–	–
Model 1	–6.06 (–9.87, –2.25)	0.002	0.419	2.384
Model 2	–6.20 (–10.02, –2.38)	0.001	0.420	2.380
Model 3	–6.26 (–10.08, –2.43)	0.001	0.600	1.668
Full-adjusted model	–6.18 (–10.01, –2.34)	0.002	0.416	2.406

Results derived from linear regression models adjusted confounders identified by DAGs and LASSO regression. Model 1 adjusted the first minimal sufficient adjustment set; model 2 adjusted the second minimal sufficient adjustment set; model 3 adjusted variables derived from LASSO selection. The full-adjusted model adjusted for all variables including age, gender, ethnicity, marital status, smoking, alcohol drinking, BMI, SBP, DBP, FPG, TG, HDL-C, LDL-C, baseline eGFR, duration of hypertension, duration of AGM, antihypertensive drugs, types of AGM, BUN, uric acid, PRA, serum potassium. VIF, variance inflation factor.