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. 2020 Jun 22;111(2):141–153. doi: 10.1007/s00392-020-01692-z

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© The Author(s) 2020, corrected publication 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Course of heart rates in patients with ivabradine or metoprolol within 60 months after HTX. Baseline heart rate after HTX indicated no significant difference between patients with ivabradine vs. metoprolol (P = 0.32). At 24-month follow up after HTX, patients receiving ivabradine showed a statistically lower heart in comparison to baseline (P < 0.01) and to patients with metoprolol at 24-month follow-up (P = 0.01). At 60-month follow up after HTX, patients receiving ivabradine kept having a statistically lower heart in comparison to baseline (P < 0.01) and to patients with metoprolol at 60-month follow-up (P < 0.01). HTX heart transplantation, *statistically significant (P < 0.05)