Table 3.
Causes of death within 5 years after HTX
| Parameter | Ivabradine | Metoprolol | Difference (%) | 95% CI | P value |
|---|---|---|---|---|---|
| (n = 50) | (n = 54) | ||||
| Transplant failure, n (%) | 0 (0.0%) | 9 (16.6%) | 16.6 | 6.6 to 26.6% | < 0.01* |
| Acute rejection, n (%) | 0 (0.0%) | 1 (1.9%) | 1.9 | − 1.7 to 5.5% | 0.33 |
| Infection/sepsis, n (%) | 4 (8.0%) | 6 (11.1%) | 3.1 | − 8.2 to 14.4% | 0.59 |
| Malignancy, n (%) | 1 (2.0%) | 0 (0.0%) | 2.0 | − 1.9 to 5.9% | 0.30 |
| Thromboembolic event/bleeding, n (%) | 0 (0.0%) | 1 (1.9%) | 1.9 | − 1.7 to 5.5% | 0.33 |
| All causes, n (%) | 5 (10.0%) | 17 (31.5%) | 21.5 | 6.6 to 36.4% | < 0.01* |
CI confidence interval, HTX heart transplantation, n = number
*Statistically significant (P < 0.05)