Figure 5.

Cardiac macrophage inflammatory mediator profile with immune cell β₂ARKO. CCR2 (A), IL1B (B), IL18 (C), TNFA (D), IL6 (E), CX3CR1 (F), IL10 (G), IGF1 (H), and TGFB (I) transcript expression from macrophages isolated from vehicle and isoproterenol-treated WT or β₂ARKO BMT mice was quantified by RT-qPCR. Values were normalized to the housekeeping gene TPT-1 and expressed relative to macrophages from vehicle-treated WT BMT mice. n = 6, two-way ANOVA, *P < 0.05. β₂ARKO, β₂-adrenergic receptor knockout; BMT, bone marrow transplant; IGF1, insulin-like growth factor 1; Iso, isoproterenol; RT-qPCR, reverse transcription quantitative PCR; TPT-1, tumor protein 1; Veh, vehicle; WT, wild-type.