Table 3.

Vaccine effectiveness against SARS-CoV-2 infection of any severity up to 9 months after full vaccination with any vaccine (>14 days after the second dose) by number of days after the second dose, according to sex, age, homemaker service, and any comorbidity at baseline

		Number of individuals	Vaccinated		Unvaccinated		Vaccine effectiveness (95% CI)
			Number of events	Incidence per 100 000 person-days	Number of events	Incidence per 100 000 person-days	Adjusted for age and baseline date	Fully adjusted*
15–30 days		1 685 948	..	..	..	..	..	..
	Men	685 354	133	1·3	1687	17·1	93% (91 to 94)	93% (91 to 94)
	Women	1 000 594	264	1·8	3032	21·1	92% (91 to 93)	92% (91 to 93)
	Age <50 years	769 391	191	1·7	3494	31·6	95% (95 to 96)	95% (94 to 95)
	Age 50–64 years	431 159	106	1·6	876	13·9	88% (86 to 90)	88% (86 to 90)
	Age 65–79 years	327 850	47	1·0	213	4·5	80% (72 to 85)	82% (75 to 88)
	Age ≥80 years	157 548	53	2·3	136	6·3	67% (55 to 76)	74% (63 to 82)
	Any comorbidity	619 248	184	1·8	897	11·7	85% (83 to 87)	86% (84 to 88)
	Homemaker service	117 684	72	2·8	68	7·9	76% (65 to 84)	76% (65 to 84)
31–60 days		1 544 326	..	..	..	..	..	..
	Men	629 873	361	1·8	2900	17·9	90% (89 to 91)	90% (89 to 91)
	Women	914 453	893	3·0	6008	25·8	88% (87 to 89)	88% (87 to 89)
	Age <50 years	704 877	706	3·1	6683	37·2	91% (91 to 92)	91% (90 to 92)
	Age 50–64 years	410 305	303	2·3	1776	15·7	85% (83 to 87)	85% (83 to 87)
	Age 65–79 years	298 770	145	1·5	315	4·2	69% (62 to 74)	71% (64 to 76)
	Age ≥80 years	130 374	100	2·1	134	5·0	69% (60 to 76)	73% (65 to 79)
	Any comorbidity	563 605	439	2·1	1571	13·2	84% (83 to 86)	85% (83 to 86)
	Homemaker service	108 919	149	2·9	64	5·1	71% (59 to 79)	70% (59 to 79)
61–120 days		1 363 616	..	..	..	..	..	..
	Men	558 636	721	2·0	2360	10·9	84% (82 to 85)	83% (82 to 85)
	Women	804 980	1715	3·1	5162	16·8	82% (81 to 83)	82% (81 to 83)
	Age <50 years	618 008	1531	3·7	5697	24·3	84% (83 to 84)	83% (82 to 84)
	Age 50–64 years	380 804	492	2·1	1510	9·5	81% (79 to 83)	81% (79 to 83)
	Age 65–79 years	260 405	227	1·2	255	2·6	66% (59 to 72)	65% (56 to 72)
	Age ≥80 years	104 399	186	2·0	60	2·0	48% (30 to 61)	50% (30 to 64)
	Any comorbidity	497 270	852	2·2	1252	8·3	79% (77 to 81)	79% (77 to 80)
	Homemaker service	101 580	247	2·5	64	3·5	64% (51 to 73)	61% (47 to 72)
121–180 days		635 402	..	..	..	..	..	..
	Men	220 596	273	1·0	97	1·2	33% (15 to 47)	29% (9 to 45)
	Women	414 806	547	1·1	302	2·1	58% (52 to 64)	54% (46 to 61)
	Age <50 years	269 241	503	1·6	293	2·7	55% (48 to 61)	51% (43 to 58)
	Age 50–64 years	115 938	161	1·0	36	1·1	40% (14 to 58)	29% (−5 to 52)
	Age 65–79 years	156 187	92	0·5	27	0·5	40% (3 to 63)	30% (−16 to 58)
	Age ≥80 years	94 036	64	0·5	43	1·3	53% (31 to 68)	46% (15 to 66)
	Any comorbidity	269 919	273	0·7	97	1·4	58% (47 to 67)	55% (42 to 65)
	Home maker service	90 347	81	0·6	24	1·5	35% (−14 to 63)	29% (−24 to 59)
>180 days		327 257	..	..	..	..	..	..
	Men	104 220	351	1·7	51	2·1	25% (0 to 45)	17% (−13 to 40)
	Women	223 037	889	2·0	172	3·1	41% (30 to 50)	34% (22 to 45)
	Age <80 years	260 172	1005	1·9	204	3·3	40% (30 to 48)	33% (21 to 43)
	Age ≥80 years	67 085	235	1·8	19	1·0	4% (−50 to 39)	5% (−53 to 41)
	Any comorbidity	160 790	536	1·6	41	1·6	22% (−8 to 43)	15% (−17 to 38)

^*Adjusted for age, baseline date, sex, homemaker service, place of birth, education, and comorbidities at baseline.