FIG. 3.

Percentage of sera showing significant elevations (values greater than 6 SEM above the means in healthy controls) of circulating mycobacterial antigens in Chilean patients with tuberculosis and in controls. See the legend to Fig. 2 and Materials and Methods for details. The percentage of sera showing significant elevation in Ag85 complex or Ag85B levels was significantly higher in patients with pulmonary tuberculosis than in healthy controls (∗∗∗, P < 0.001; ∗∗, P < 0.002 [Fisher exact test]). Sensitivity was significantly increased by combinatorial consideration of reagent results (P < 0.02, Fisher exact test).